Genquire: genome annotation browser/editor
نویسندگان
چکیده
منابع مشابه
Annotation confidence score for genome annotation: a genome comparison approach
MOTIVATION The massively parallel sequencing technology can be used by small research labs to generate genome sequences of their research interest. However, annotation of genomes still relies on the manual process, which becomes a serious bottleneck to the high-throughput genome projects. Recently, automatic annotation methods are increasingly more accurate, but there are several issues. One im...
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A t the time that Watson and Crick proposed a structure for DNA, a visionary might have suggested that the complete genetic sequence of an organism would eventually be known. However, nobody could have realistically proposed that machines could automatically indicate gene functions. Yet precisely this has been achieved: with no laboratory experiments at all, the roles of most genes in several o...
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The concept of the gene plays a fundamental role both in the interpretation and in the organization and storage of molecular biology data. Genes are treated as if they were unambiguously characterized physical entities with clearly defined measurable properties. The ubiquitous usage of genes in current bio-databases reinforces this perception. A closer look at the data models and the ongoing di...
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Understanding the genetic content of a genome is a very important but challenging task. One of the most effective methods to annotate a genome is to compare it to the genomes that are already sequenced and annotated. This chapter is to survey systems that can be used for annotating genomes by comparing multiple genomes and discusses important issues in designing genome comparison systems such a...
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The process of annotating prokaryotic genomes includes prediction of protein-coding genes, as well as other functional genome units such as structural RNAs, tRNAs, small RNAs, pseudogenes, control regions, direct and inverted repeats, insertion sequences, transposons, and other mobile elements. Bacterial and archaeal genomes have the considerable advantage of usually lacking introns, which subs...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2002
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/18.10.1398